Asante Kotoko, have been knocked out from the MTN FA Cup competition after suffering defeat to Berekum Chelsea on penalties in the quarter finals.
The Porcupine Warriors’ season has ended without a trophy after losing the Ghana Premier League title to rivals Hearts of Oak a fortnight ago.
The defending champions had an opportunity to win the game against Chelsea in the first half when they were awarded a penalty by the referee, but Brazilian playmaker Fabio Gama missed from the spot.
The game was then forced into penalty shootouts after 120 minutes of football at the Obuasi Len Clay stadium.
Kotoko defender Wahab Adams missed his spot kick allowing Berekum Chelsea to take the lead in the shoot outs.
Berekum Chelsea talisman Stephen Amankona scored the winner as the Blues advance to the semi finals.
Meanwhile, Accra Hearts of Oak beat Elmina Sharks 1-0, courtesy an extra time goal from defender Caleb Amankwah.
On Saturday, Ashantigold defeated lower tier side Kintampo Top Stars before Medeama SC survived a scare from Attram De Visser, after the Division Two side twice came from behind to peg the two times champions.
Prince Opoku Agyemang scored the winner in extra time to set up a date with Hearts of Oak in the semi finals.
Berekum Chelsea will engage Ashantigold in the other semi final match.